Biology may make certain PTSD patients unresponsive to behavioral therapy

How well-connected a particular brain network is, and how successfully memories are formed, may determine which patients with post-traumatic stress disorder benefit from behavioral therapy, researchers at the Stanford University School of Medicine have found.

The finding could indicate a biological subtype of PTSD whose clinical relevance only becomes obvious when patients undergo treatment, the researchers said. Furthermore, by replicating their results across a diverse range of patients, the researchers were able to clearly and objectively characterize a biological signature in PTSD patients who differ in their response to behavioral therapy.  more

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The Treatment of Hallucinations in Schizophrenia Spectrum Disorders

Schizophrenia can be accompanied by hallucinations in any of the sensory modalities. In 70% of the cases they are auditory in nature, and in 50% of those cases visual hallucinations are also experienced at some point. Other types of hallucination are less prevalent. But whatever the sensory modality in which they are experienced, hallucinations can be such a burden that they require expert treatment. Treatment usually consists of psychoeducation, medication, psychosocial interventions, psychotherapy, and in some instances transcranial magnetic stimulation (TMS) or electroconvulsive therapy (ECT).

The present article will focus on medication, cognitive-behavioral therapy (CBT), TMS, and ECT. We will summarize the existing literature and offer recommendations for the treatment of hallucinations in schizophrenia.  more

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