When people combine stimulants with alcohol, Karpyak says, the rush of energy and seeming invincibility leads them to consume significant amounts of alcohol—much larger than they’re used to or normally capable of, which leads to “miscalculations.” But of greater concern than alcohol and stimulants is actually alcohol and sedatives, or a combination of sedatives with each other.
You’ve probably heard that combining alcohol and Ambien can make you act weird—loopy, irrational, generally embarrassing—because people are always getting kicked off airplanes after trying too hard to relax. (Occasionally a nun will consume a glass of altar wine and then try to fall asleep before waking up in a different state with no recollection of how she got there or how she managed to crash a car into a building.) Benzodiazepines, the popular class of medication for anxiety, are also frequently prescribed for insomnia. These include Klonopin, Valium, Ativan, and, of course, America’s long-standing psychiatric favorite, Xanax. more